Calcs

ACTION ICU Score for Intensive Care in NSTEMI

Predicts the risk of ICU-level complications in initially uncomplicated NSTEMI patients

AUB-HAS2 Cardiovascular Risk Index

Predicts 30-day risk of death, MI, or stroke in patients undergoing non-cardiac surgery

Bova Score for Pulmonary Embolism Complications

Predicts risk of PE-related complications in hemodynamically stable patients

Caprini Score for Venous Thromboembolism

Stratifies VTE risk in surgical patients to guide thromboprophylaxis

CHA₂DS₂-VASc Score

Stroke risk stratification in atrial fibrillation

CHADS₂ Score

Original stroke risk score for atrial fibrillation (predecessor to CHA₂DS₂-VASc)

Corrected QT Interval (QTc)

Heart rate-corrected QT interval using Bazett, Fridericia, and Framingham formulas

DAPT Score

Determines benefit of prolonged dual antiplatelet therapy (>12 months) after coronary stenting

EUROMACS Right Heart Failure Risk Score

Predicts risk of right heart failure after left ventricular assist device (LVAD) implantation

Fick Cardiac Output Calculation

Calculates cardiac output and cardiac index using the Fick principle from oxygen consumption and arteriovenous oxygen content difference

Framingham Risk Score (CHD)

Estimates 10-year risk of coronary heart disease events

GRACE Score (ACS)

Global Registry of Acute Coronary Events — in-hospital and 6-month mortality

Gupta Perioperative Risk for MICA

Estimates 30-day risk of myocardial infarction or cardiac arrest after non-cardiac surgery

H2FPEF Score for Heart Failure with Preserved EF

Estimates probability of HFpEF in patients with unexplained dyspnea using clinical and echocardiographic variables

HAS-BLED Score

Major bleeding risk assessment for patients on anticoagulation

HEART Pathway (Early Discharge)

Combines the HEART score with serial troponins to identify chest-pain patients safe for early discharge

HEART Score

Risk stratification for acute coronary syndrome in chest pain patients

Killip Classification

Bedside classification of heart failure severity after acute MI

Mean Arterial Pressure (MAP)

Estimates average arterial pressure during a cardiac cycle

Modified Sgarbossa Criteria

Diagnoses acute MI in patients with left bundle branch block or ventricular paced rhythm using ECG criteria

NYHA Heart Failure Classification

Classifies functional capacity and symptom severity in heart failure

Ottawa Heart Failure Risk Scale (OHFRS)

Identifies emergency department patients with acute heart failure at high risk of serious adverse events within 30 days

PERC Rule

Pulmonary Embolism Rule-out Criteria — excludes PE without testing

PESI (Pulmonary Embolism Severity Index) Score

Predicts 30-day mortality in acute pulmonary embolism and stratifies patients for safe outpatient treatment

Revised Cardiac Risk Index (RCRI)

Estimates risk of major cardiac complications in non-cardiac surgery

SAMe-TT₂R₂ Score (DOAC vs. Warfarin)

Predicts quality of warfarin anticoagulation control in AF to guide DOAC vs. VKA selection

sPESI (Simplified PESI)

Simplified Pulmonary Embolism Severity Index for 30-day mortality risk

TIMI Score (NSTEMI/UA)

Risk stratification for unstable angina and NSTEMI

US (MEDPED) Criteria for Familial Hypercholesterolemia

Diagnoses familial hypercholesterolemia (FH) using age-specific total cholesterol thresholds based on family relationship to an affected individual

Villalta Score for Post-Thrombotic Syndrome (PTS)

Diagnoses and grades the severity of post-thrombotic syndrome (PTS) after deep vein thrombosis using five patient-reported symptoms, six clinician-assessed signs, and presence or absence of venous ulceration

Wells Score for DVT

Clinical prediction rule for deep vein thrombosis probability

Wells' Criteria for PE

Clinical prediction rule for pulmonary embolism probability

⚕ Critical Care / ICU

APACHE II

Acute Physiology and Chronic Health Evaluation for ICU mortality prediction

Behavioral Pain Scale (BPS)

Quantifies pain in intubated, mechanically ventilated patients who cannot self-report

Braden Score for Pressure Ulcer Risk

Assesses risk of developing pressure ulcers/injuries in hospitalized patients

Clinical Pulmonary Infection Score (CPIS) for VAP

Diagnoses ventilator-associated pneumonia using clinical, radiographic, and microbiological criteria

Edmonton Symptom Assessment System — Revised (ESAS-r)

Patient-rated 0–10 numeric scale assessing 9 common symptoms in palliative and cancer care

GO-FAR Score for In-Hospital CPR Outcomes

Predicts survival with favorable neurological outcome after in-hospital cardiac arrest treated with CPR

HACOR Score for NIV Failure

Predicts failure of noninvasive ventilation (NIV) in hypoxemic patients at 1–2 hours after initiation

Intraoperative Fluid Dosing in Adult Patients

Estimates IV fluid requirements during surgery based on weight, fasting duration, surgery type, and blood loss

NEWS (National Early Warning Score)

Detects clinical deterioration and predicts adverse outcomes in hospitalized patients

Nonverbal Pain Scale (NVPS)

Quantifies pain in non-communicative or intubated patients using behavioral and physiological indicators

qSOFA (Quick SOFA)

Bedside sepsis screening tool — no lab tests required

RASS

Richmond Agitation-Sedation Scale for ICU sedation assessment

RESP (Respiratory ECMO Survival Prediction) Score

Predicts in-hospital survival for adult patients initiated on venovenous ECMO for acute respiratory failure

RSBI (Rapid Shallow Breathing Index)

Predicts success of ventilator weaning — f/VT ratio

SAPS II

Simplified Acute Physiology Score II — ICU mortality prediction.

Simplified Acute Physiology Score (SAPS) 3

Predicts ICU hospital mortality using 20 variables collected at or within 1 hour of ICU admission in critically ill adults

SIRS Criteria

Systemic Inflammatory Response Syndrome identification

SOFA Score

Sequential Organ Failure Assessment for ICU mortality prediction

◎ Respiratory / Pulmonology

A-a Gradient

Alveolar-arterial oxygen gradient for hypoxemia evaluation

ARISCAT Score for Postoperative Pulmonary Complications

Predicts risk of postoperative pulmonary complications in non-cardiac surgery

Asthma Impairment and Risk Questionnaire (AIRQ)

Measures impairment and risk associated with asthma over the past 4 weeks

BAP-65 Score for Acute Exacerbation of COPD

Predicts in-hospital mortality in acute exacerbations of COPD

COPD Assessment Test (CAT)

Quantifies COPD symptom impact on health status and quality of life

CURB-65

Community-acquired pneumonia severity score for disposition decisions

du Bois Score for IPF Mortality

Predicts 1-year and 2-year mortality in idiopathic pulmonary fibrosis using clinical and spirometric variables

GOLD Criteria for COPD

Classifies COPD airflow obstruction severity and assigns ABCD groups to guide pharmacological therapy

Hestia Criteria for Outpatient PE Treatment

Identifies patients with acute PE safe for outpatient anticoagulation treatment

mMRC Dyspnea Scale

Modified Medical Research Council scale for grading breathlessness severity

Modified Asthma Predictive Index (mAPI)

Predicts future asthma diagnosis in young children with recurrent wheezing using major and minor risk criteria

MuLBSTA Score for Viral Pneumonia Mortality

Predicts 90-day mortality in adults hospitalized with viral pneumonia using six clinical and laboratory parameters

Pediatric Asthma Score (PAS)

Bedside score stratifying severity of asthma exacerbations in children to guide acute management

PIRO Score for CAP

Predicts ICU mortality in community-acquired pneumonia using Predisposition, Insult, Response, and Organ dysfunction domains

PSI / PORT Score

Pneumonia Severity Index for community-acquired pneumonia risk stratification.

Quick COVID-19 Severity Index (qCSI)

Predicts risk of critical respiratory illness within 24 hours in emergency department patients with COVID-19 using three clinical variables

Respiratory Distress Observation Scale (RDOS)

Quantifies respiratory distress severity in patients unable to self-report using eight observable behavioral and physiological indicators

Roth Score for Hypoxia Screening

Screens for hypoxia by having the patient count aloud in a single breath — a count <10 or time >10 seconds suggests SpO₂ <95%

ROX Index

Predicts success/failure of high-flow nasal cannula to avoid intubation

SMART-COP

Predicts need for intensive respiratory or vasopressor support in community-acquired pneumonia.

STOP-BANG Questionnaire

Screens for obstructive sleep apnea risk using eight validated clinical questions in adults, guiding pre-operative and clinical sleep evaluation

⟁ Neurology / Stroke

Abbreviated Mental Test 4 (AMT-4)

Rapid 4-item cognitive screening for delirium and dementia in elderly patients

ABC/2 Formula for ICH Volume

Estimates intracerebral hemorrhage volume from CT measurements

ABCD² Score

Stroke risk stratification after transient ischemic attack (TIA)

ASCOD Algorithm for Ischemic Stroke

Assigns a phenotype and probability of causality across five etiologic domains for ischemic stroke

ASPECTS

Alberta Stroke Program Early CT Score — ischemic stroke CT scoring.

Berg Balance Scale (BBS)

Assesses static and dynamic balance and predicts fall risk in older adults

Glasgow Coma Scale (GCS)

Standardized assessment of consciousness level after brain injury

Hunt and Hess Classification

Clinical grading scale for aneurysmal subarachnoid hemorrhage severity and surgical risk

ICH Score

30-day mortality prediction in spontaneous intracerebral hemorrhage.

Migraine Treatment Optimization Questionnaire-4 (mTOQ-4)

Determines the effectiveness of current acute migraine treatment using 4 validated questions

Modified Fisher Grading Scale for SAH

Grades CT findings in subarachnoid hemorrhage to predict risk of cerebral vasospasm and delayed ischemic neurological deficit

Modified Rankin Scale for Neurologic Disability

Grades degree of disability or dependence in daily activities after stroke or other neurological conditions

Myasthenia Gravis Activities of Daily Living (MG-ADL)

Patient-reported 8-item scale quantifying MG symptom severity across bulbar, respiratory, and limb function domains

NIH Stroke Scale (NIHSS)

Quantifies stroke severity to guide acute treatment decisions

Pain Assessment in Advanced Dementia Scale (PAINAD)

Assesses pain intensity in patients with advanced dementia through behavioral observation across five domains

PFO-Associated Stroke Causal Likelihood (PASCAL)

Classifies the likelihood that a patent foramen ovale (PFO) caused an ischemic stroke using anatomical and clinical features

Pittsburgh Response to Endovascular therapy (PRE) Score

Predicts 90-day functional independence after endovascular therapy for acute ischemic stroke using pre-treatment variables

RCVS² Score

Distinguishes reversible cerebral vasoconstriction syndrome (RCVS) from other intracranial arteriopathies including primary angiitis of the CNS (PACNS)

Schwab and England Activities of Daily Living Scale

Grades functional independence in activities of daily living in Parkinson's disease patients on a 0–100% scale

tPA Dose for Ischemic Stroke Calculator

Calculates weight-based alteplase (tPA) total dose, IV bolus, and infusion for acute ischemic stroke per AHA/ASA guidelines

tPA Dose for Ischemic Stroke Calculator

Calculates alteplase (tPA) total dose, IV bolus, and infusion volumes for acute ischemic stroke thrombolysis based on patient weight

Webster Rating Scale for Parkinson's Disease

Quantifies disability severity in Parkinson's disease across ten motor and functional domains, stratifying disease into mild, moderate, and severe stages

✚ Surgery / Trauma / Emergency

Alvarado Score (MANTRELS)

Clinical prediction rule for acute appendicitis

Appendicitis Inflammatory Response (AIR) Score

Diagnoses acute appendicitis using clinical and laboratory findings

Blast Lung Injury Severity Score

Stratifies primary blast lung injuries to guide ventilator management and predict ARDS risk

Canadian CT Head Rule

Identifies adults with minor head injury who need CT imaging

CholeS Score for Laparoscopic Cholecystectomy Duration

Predicts operative duration of elective laparoscopic cholecystectomy

CholeS Score for Laparoscopic Cholecystectomy Duration

Predicts operative time >90 minutes for elective or emergency laparoscopic cholecystectomy

ISS — Injury Severity Score

Anatomical scoring system for trauma severity based on AIS regions.

LRINEC Score for Necrotizing Soft Tissue Infection

Laboratory-based score to differentiate necrotizing fasciitis from other severe soft tissue infections

NEXUS C-Spine Rule

Identifies trauma patients who do NOT need cervical spine imaging

Parkland Formula (Burns)

Fluid resuscitation calculation for burn patients

PedSRC Rule for Blunt Abdominal Trauma

Identifies children at very low risk (<0.1%) of intra-abdominal injury after blunt abdominal trauma, potentially avoiding CT

Preoperative Mortality Predictor (PMP) Score

Estimates 30-day perioperative mortality risk in patients undergoing general surgery using five preoperative clinical variables

Revised Tokuhashi Scoring System

Predicts survival and guides surgical decision-making in patients with spinal metastases using six preoperative clinical variables

Rule of Nines (Burns)

Rapid estimation of total body surface area (TBSA) burned

Shock Index

Heart rate / systolic BP ratio for hemodynamic instability detection

Subaxial Injury Classification (SLICS)

Classifies subaxial cervical spine (C3–C7) injuries and guides surgical vs. conservative management using morphology, DLC integrity, and neurological status

Thoracolumbar Injury Classification (TLICS)

Classifies thoracolumbar spine injuries and guides surgical vs. conservative management using injury morphology, posterior ligamentous complex integrity, and neurological status

Wisconsin Criteria for Maxillofacial CT

Clinical decision rule identifying patients who require computed tomography of the face after facial trauma, stratifying high-risk features to guide appropriate imaging

⬡ Gastroenterology / Hepatology

ABIC Score for Alcoholic Hepatitis

Predicts short-term survival in patients with alcoholic hepatitis

AIMS65 Score

Predicts in-hospital mortality from acute upper GI bleeding before endoscopy

BISAP Score

Early severity prediction in acute pancreatitis within 24 hours

Child-Pugh Score

Classification of severity of cirrhosis and hepatic dysfunction

Crohn's Disease Activity Index (CDAI)

Measures Crohn's disease activity over 7 days to classify remission, mild, moderate, or severe disease

FIB-4 Index

Non-invasive liver fibrosis assessment using routine lab values

Forrest Classification of Upper GI Bleeding

Endoscopic classification of peptic ulcer bleeding stigmata to stratify rebleeding risk and guide endoscopic therapy

Glasgow-Blatchford Bleeding Score (GBS)

Predicts need for intervention in acute upper GI bleeding before endoscopy

Mayo Score / Disease Activity Index (DAI) for Ulcerative Colitis

Quantifies disease activity in ulcerative colitis using clinical and endoscopic parameters to guide treatment decisions

MELD Score for End-Stage Liver Disease Mortality (MELD 3.0)

Estimates 90-day mortality in end-stage liver disease using the updated MELD 3.0 formula incorporating sex and sodium

MELD-Na Score

Model for End-Stage Liver Disease with sodium correction

Oakland Score for Safe Discharge After Lower GI Bleed

Identifies patients with acute lower GI bleeding who can be safely discharged without inpatient intervention

PELD Creatinine (Pediatric End-Stage Liver Disease)

Updated PELD formula incorporating serum creatinine for pediatric liver transplant waitlist prioritization

PELD Score (Younger Than 12)

Classic pediatric MELD equivalent for prioritizing liver transplant in children under 12 years with end-stage liver disease

Prague C & M Classification for Barrett's Esophagus

Standardized endoscopic grading of Barrett's esophagus extent using circumferential (C) and maximal (M) measurements in cm from the gastroesophageal junction

R-Factor (Hepatotoxicity Pattern)

Classifies drug-induced liver injury pattern as hepatocellular, cholestatic, or mixed

Ranson's Criteria (Pancreatitis)

Predicts severity and mortality in acute pancreatitis at admission and 48 hours

Rome IV - Child Functional Nausea and Vomiting

Applies Rome IV H2b criteria to diagnose Functional Nausea and Functional Vomiting in children and adolescents aged 4–18 years

Rome IV - Fecal Incontinence

Applies Rome IV C7 criteria to diagnose functional fecal incontinence in adults, with classification by mechanism and severity

Rome IV - Functional Chest Pain

Applies Rome IV B3 criteria to diagnose functional chest pain of presumed esophageal origin after cardiac and esophageal causes have been excluded

Rome IV - Functional Pancreatic Sphincter of Oddi Disorder

Applies Rome IV E2 criteria to diagnose Functional Pancreatic Sphincter of Oddi Disorder in adults with recurrent unexplained pancreatitis after exclusion of structural, metabolic, and toxic causes

Rome IV - Opioid-Induced Constipation (OIC)

Applies Rome IV criteria to diagnose opioid-induced constipation and guides evidence-based management with laxatives, PAMORAs, and dose optimisation

Rome IV - Reflux Hypersensitivity (B2)

Applies Rome IV B2 criteria to diagnose reflux hypersensitivity — heartburn or chest pain with symptom-reflux correlation on pH-impedance monitoring despite normal esophageal acid exposure

West Haven Criteria for Hepatic Encephalopathy

Grades severity of hepatic encephalopathy (HE) from covert to coma based on clinical neuropsychiatric findings

◈ Nephrology / Fluids / Acid-Base

Anion Gap

Serum anion gap calculation for metabolic acidosis differential

Bicarbonate Replacement

Calculates NaHCO₃ deficit and replacement dose for metabolic acidosis.

BUN/Creatinine Ratio

Differentiates prerenal from intrinsic renal causes of azotemia

CKD-EPI (eGFR)

Estimated glomerular filtration rate using the 2021 CKD-EPI equation

Corrected Sodium (for Hyperglycemia)

Adjusts measured sodium for the dilutional effect of hyperglycemia

Creatinine Clearance (Cockcroft-Gault)

Estimates CrCl for drug dose adjustments

FENa

Fractional Excretion of Sodium — differentiates prerenal from intrinsic AKI

FEUrea

Fractional Excretion of Urea — AKI differential when on diuretics

Free Water Deficit

Estimates free water deficit for hypernatremia correction

McMahon Score for Rhabdomyolysis

Predicts mortality or acute kidney injury requiring dialysis in patients with rhabdomyolysis

Potassium Replacement Calculator

Estimates KCl dose needed to correct hypokalemia

Revised Schwartz Equation for GFR (2009)

Estimates glomerular filtration rate in children and adolescents using height and serum creatinine (bedside 2009 CKiD equation)

Serum Osmolality (Calculated) & Osmolar Gap

Calculated serum osmolality and osmolar gap for toxic alcohol evaluation

Sodium Correction Rate (Adrogué-Madias)

Estimates the effect of 1L of IV fluid on serum sodium for safe correction

Urine Output and Fluid Balance

Calculates urine output rate (mL/kg/hr) and net fluid balance from intake and output data, with AKI oliguria staging

◇ Endocrinology / Metabolic

ADA Type 2 Diabetes Risk Test

Identifies adults at risk for type 2 diabetes or prediabetes using a validated point-based questionnaire

BeAM Value

Calculates the difference between bedtime and morning fasting blood glucose to assess basal insulin effect

Burch-Wartofsky Point Scale (BWPS) for Thyrotoxicosis

Estimates the likelihood of thyroid storm in patients with thyrotoxicosis

Canadian Diabetes Risk Assessment Questionnaire (CANRISK)

Estimates 10-year risk of developing type 2 diabetes or prediabetes in Canadian adults

Corrected Calcium

Adjusts total calcium for hypoalbuminemia

Diabetes Distress Scale (DDS17)

Assesses emotional distress specific to living with diabetes across four subscales

Diabetic Ketoacidosis Mortality Prediction Model (DKA MPM) Score

Predicts in-hospital mortality and classifies severity of diabetic ketoacidosis at presentation

Edmonton Obesity Staging System (EOSS)

Stratifies obesity-related disease burden and functional limitations across five stages to guide treatment intensity

Insulin Correction & Sensitivity Calculator

Calculates insulin sensitivity factor, correction dose, and I:C ratio

International Diabetes Federation-Ramadan Alliance (IDF-DAR)

Stratifies risk of fasting during Ramadan in patients with diabetes to guide individualized management

◉ Hematology / Oncology

4Ts Score (HIT)

Pre-test probability of heparin-induced thrombocytopenia

Absolute Neutrophil Count (ANC)

Calculates absolute neutrophil count to assess neutropenia severity

BALL Score for Relapsed/Refractory CLL

Prognostic score predicting survival in relapsed/refractory CLL patients receiving targeted therapy

Follicular Lymphoma International Prognostic Index (FLIPI)

Five-factor prognostic scoring system for follicular lymphoma predicting overall survival

GELF Criteria for Follicular Lymphoma

Identifies patients with high tumor burden follicular lymphoma requiring immediate systemic therapy

Genetically Inspired Prognostic Scoring System (GIPSS) for PMF

Predicts overall survival in primary myelofibrosis using karyotype and somatic mutation data

HScore for Reactive Hemophagocytic Syndrome

Estimates the probability of reactive hemophagocytic syndrome (HPS/HLH) from clinical and laboratory parameters

IMDC Risk Model for Metastatic RCC

Stratifies prognosis in metastatic renal cell carcinoma (Heng/IMDC criteria)

IMPROVE Risk Score for VTE

Predicts 3-month VTE risk in hospitalized medical patients to guide thromboprophylaxis decisions

IMPROVE Risk Score for VTE

Predicts 3-month risk of venous thromboembolism in medically ill hospitalized patients

International Prognostic Index for CLL (CLL-IPI)

Stratifies chronic lymphocytic leukemia into four risk groups using five weighted prognostic factors

MASCC Risk Index for Febrile Neutropenia

Identifies low-risk cancer patients with febrile neutropenia who may safely receive outpatient oral antibiotic therapy

Mentzer Index

Differentiates beta-thalassemia trait from iron deficiency anemia using MCV and RBC count

Mutation-Adjusted Risk Score (MARS) for Advanced Systemic Mastocytosis

Stratifies prognosis in advanced systemic mastocytosis using S/A/R mutation status and clinical-laboratory parameters

Padua Prediction Score for Risk of VTE

Stratifies VTE risk in hospitalized medical patients to guide thromboprophylaxis decisions

PREVAIL Model for Prostate Cancer Survival

Predicts overall survival in chemotherapy-naive men with metastatic castration-resistant prostate cancer (mCRPC) receiving novel androgen receptor inhibitors

Revised IPSS-R for Myelodysplastic Syndrome (MDS)

Stratifies MDS prognosis into 5 risk categories using cytogenetics, bone marrow blasts, hemoglobin, platelets, and ANC

Sokal Index for CML

Calculates baseline prognostic risk in chronic myeloid leukemia (CML) using age, spleen size, platelet count, and peripheral blast percentage

Therapeutic Plasmapheresis Calculator

Calculates plasma volume, exchange volume per session, and fraction of pathological substance remaining after therapeutic plasma exchange (TPE)

⬢ Infectious Disease

ATLAS Score for Clostridioides difficile Infection

Predicts treatment failure in Clostridioides difficile infection using five clinical and laboratory variables

Centor Score (Modified/McIsaac)

Likelihood of streptococcal pharyngitis and need for testing/antibiotics

DRIP Score

Predicts drug-resistant pathogen risk in community-onset pneumonia to guide antibiotic selection

FeverPAIN Score for Strep Pharyngitis

Predicts likelihood of Group A Streptococcal pharyngitis to guide antibiotic prescribing

Rule of 7s for Lyme Meningitis

Distinguishes Lyme meningitis from aseptic meningitis in children with CSF pleocytosis using three clinical criteria based on the number 7

℞ Pharmacology / Medications

Atropine Dosing for Cholinesterase Inhibitor Toxicity

Calculates initial atropine dose and titration guidance for organophosphate, carbamate, or nerve agent poisoning

Corticosteroid Equivalency Converter

Converts doses between systemic corticosteroids based on anti-inflammatory potency equivalence

Dose by BSA (mg/m²)

Converts BSA-based dosing (mg/m²) to actual dose using patient height and weight

Drug Dose by Weight (mg/kg → mL)

Converts weight-based dosing to administered volume using drug concentration

Drug Infusion Rate Calculator

Converts mcg/kg/min or mg/hr dose orders to pump rate (mL/hr)

Heparin Infusion Calculator

Weight-based heparin bolus and drip rate calculator for VTE and ACS.

IV Drip Rate Calculator

Calculates drops/min for gravity infusions and mL/hr for pump infusions

Pharmacogenomic Dosing Advisor (CPIC / DPWG / FDA / EMA)

Genotype-guided dose, avoidance and switch recommendations across 60 drug–gene pairs

Vancomycin AUC Dosing

AUC/MIC-guided vancomycin dosing and monitoring per ASHP/IDSA/SIDP 2020 guidelines.

Vasopressor Converter

Convert vasopressor doses between mcg/kg/min, mg/hr, and mL/hr.

Warfarin Pharmacogenetic Dosing (Gage Algorithm)

Estimates therapeutic daily warfarin dose using genetics (CYP2C9/VKORC1) and clinical factors

◐ Pediatrics / Neonatology

◐ Pediatrics · App

NeuroDev Guidance

Growth charts and neurodevelopmental surveillance with a cited, level-based recommendation for specialist assessment

APGAR Score

Rapid assessment of newborn clinical status at birth

Cornell Assessment of Pediatric Delirium (CAPD)

Nurse-administered delirium screening tool for critically ill children across all developmental stages

Corrected Age for Preterm Infants

Corrected (adjusted) age from gestational age at birth and chronological age, with the period over which correction applies

Eat, Sleep, Console (ESC) Assessment

Function-based neonatal opioid withdrawal tool to guide pharmacotherapy decisions

FLACC Pain Scale (Face, Legs, Activity, Cry, Consolability)

Behavioral pain assessment scale for non-verbal or pre-verbal children and adults unable to self-report pain

Kawasaki Disease Diagnostic Criteria

Diagnoses Kawasaki Disease and incomplete Kawasaki Disease using classic AHA criteria and supplemental laboratory/echo findings

M-CHAT-R/F Score Interpretation

Applies the official M-CHAT-R/F scoring algorithm to the total and Follow-Up scores (items not reproduced)

Maintenance IV Fluids (4-2-1 Rule)

Holliday-Segar method for calculating maintenance fluid requirements

Mid-Parental (Target) Height

Expected adult height range from the parents' heights (Tanner method, ±8.5 cm)

PECARN Pediatric Head Injury Rule

Identifies children at very low risk for clinically important traumatic brain injury

Pediatric ETT Size

Endotracheal tube size estimation by age for pediatric intubation

Pediatric SIRS, Sepsis, and Septic Shock

Applies age-specific IPSCC 2005 criteria to diagnose SIRS, sepsis, severe sepsis, and septic shock in children

Standard Score Converter (Composite, T, Scaled, z)

Converts norm-referenced test scores to z-score and percentile, with publisher-cited labels only

Step-by-Step Approach to Febrile Infants

Sequential algorithm to identify low-risk febrile infants 22–90 days old for serious bacterial infection, guiding safe outpatient management

◑ Obstetrics / Maternal

◑ Obstetrics · App

Prenatal Guidance

Gestational age and due date by LMP, IVF/IUI dates or ultrasound (Robinson–BMUS, INTERGROWTH-21st), with the antenatal recommendations for that week compiled from WHO, national authorities and US societies — every body side by side, every statement cited

Bishop Score

Cervical readiness assessment for labor induction success prediction

Fetal Biophysical Profile (BPP) Score

Assesses fetal wellbeing and risk of fetal distress using five ultrasound and NST parameters

First Trimester Twin MoM Adjustment

Corrects PAPP-A and free beta-hCG MoM values for twin pregnancies by chorionicity

Intrauterine RBC Transfusion Dosage

Estimates the volume of packed red blood cells for intrauterine transfusion based on fetal weight and hematocrit values

Risk of Malignancy Index (RMI) for Ovarian Cancer

Combines ultrasound features, menopausal status, and CA-125 to estimate the risk of malignancy in an adnexal mass before surgery

VBAC Risk Score (Flamm Model)

Predicts the likelihood of successful vaginal birth after cesarean (VBAC) using six antepartum and intrapartum variables from the Flamm 1997 admission scoring system

▣ Nutrition / Enteral / TPN

GIR (Glucose Infusion Rate)

Glucose/dextrose infusion rate in mg/kg/min for TPN and IV dextrose management

Harris-Benedict (BMR/TEE)

Basal metabolic rate and total energy expenditure estimation

NUTRIC Score

Nutritional Risk in the Critically Ill — identifies ICU patients who benefit from aggressive nutrition.

Nutritional Risk Index (NRI)

Quantifies malnutrition risk using serum albumin and weight change from usual body weight

◎ Psychiatry / Mental Health

Behavioral Activity Rating Scale (BARS)

Seven-point observational scale for rapid bedside assessment of agitation severity and treatment response

Brief Alcohol Withdrawal Scale (BAWS)

Monitors severity of alcohol withdrawal symptoms to guide pharmacological treatment

CAGE Questionnaire

Brief 4-item screening tool for alcohol use disorder

CIWA-Ar

Clinical Institute Withdrawal Assessment for Alcohol — revised

Clinical Opiate Withdrawal Scale (COWS)

Rates the severity of opioid withdrawal symptoms to guide clinical management

Columbia Suicide Severity Rating Scale (C-SSRS)

Standardized assessment of suicidal ideation and behavior severity

Current Opioid Misuse Measure (COMM)

Identifies aberrant medication-related behaviors in patients on long-term opioid therapy for chronic non-cancer pain

Danger Assessment Tool for Domestic Abuse

Predicts risk of being killed or nearly killed by an intimate partner in a violent relationship

DIRE Score for Opioid Treatment

Predicts patient suitability and compliance for long-term opioid therapy in chronic non-cancer pain

Edinburgh Postnatal Depression Scale (EPDS)

10-item self-report screening tool for postpartum depression in mothers and fathers

GAD-7

Screening and severity measure for generalized anxiety disorder

Glasgow Modified Alcohol Withdrawal Scale (GMAWS)

Monitors alcohol withdrawal severity to guide benzodiazepine dosing in clinical settings

HEADS-ED

Pediatric emergency department mental health screening tool — identifies youth requiring urgent psychiatric consultation

Major Depression Index (MDI)

Screens for and measures severity of major depressive disorder using ICD-10 and DSM-IV diagnostic criteria

Montgomery-Åsberg Depression Rating Scale (MADRS)

Clinician-rated 10-item scale measuring severity of depressive episodes in adults across key symptom domains

PHQ-9 (Patient Health Questionnaire)

Depression severity screening and monitoring tool

Primary Care PTSD Screen for DSM-5 (PC-PTSD-5)

5-item self-report screen for PTSD in primary care settings, aligned with DSM-5 symptom clusters

Short Michigan Alcoholism Screening Test (SMAST)

Screens for alcohol use disorder with 13 yes/no questions; score ≥3 indicates probable alcohol problem

⧖ Clinical Genetics · App

Stanford Sleepiness Scale

Rates current subjective sleepiness on a 7-point scale to assess momentary alertness and guide safe activity decisions

◻ Dermatology

EASI Score (Eczema Area and Severity Index)

Quantifies atopic dermatitis severity across four body regions for clinical and research use

◻ Dermatology

Psoriasis Area and Severity Index (PASI)

Quantifies psoriasis severity and body surface area involvement across four anatomical regions to generate a composite score from 0 to 72

◻ Dermatology

Scoring Mastocytosis (SCORMA) Index

Quantifies severity of cutaneous mastocytosis by combining skin lesion morphology and area with systemic symptom burden

◻ Dermatology

SCORTEN

Severity-of-illness score for toxic epidermal necrolysis (TEN/SJS)

⧖ Clinical Genetics

GenePedigree

Pedigree editor with standardized NSGC nomenclature, 2D editing, 3D view and multi-format import and export

⧖ Clinical Genetics · App

Prenatal Guidance

17q21.31 Microdeletion Risk (Koolen-de Vries)

Estimates KdVS risk based on parental H1/H2 inversion genotypes using Koolen et al. Bayesian model

ABC System for Genetic Variant Classification

Stepwise functional (A) → clinical (B) → comment (C) classification for any type of genetic variant (Houge et al. 2021/2024)

ACMG-AMP 2015 Variant Pathogenicity Classifier

Standardized 5-tier classification of sequence variants per ACMG/AMP 2015 guidelines with VUS sub-classification

AMP/ASCO/CAP Somatic Variant Tier Classification

Four-tier clinical-actionability classification of somatic variants in cancer (Li et al. 2017)

Bayesian Conditional Risk (Age-Adjusted Penetrance)

Adjusts prior genetic risk downward based on age-specific penetrance in asymptomatic individuals

ClinGen CNV Classification — Copy-Number GAIN

Official ACMG/ClinGen point-based scoring for a constitutional copy-number gain, with assignable points per criterion

ClinGen CNV Classification — Copy-Number LOSS

Official ACMG/ClinGen point-based scoring for a constitutional copy-number loss, with assignable points per criterion

ClinGen SVI / VCEP Points — Bayesian Variant Classifier

Point-based ACMG/AMP classification with criterion strength modulation, as used by ClinGen VCEPs

CNV Analytical Classification System

ACMG/ClinGen-inspired scoring for constitutional Copy Number Variants

Coefficient of Consanguinity & Inbreeding (F)

Calculates the inbreeding coefficient F and reproductive risk for consanguineous unions

Cohen & Daniel Viability Thresholds

Evaluates fetal survival potential of chromosome imbalances in reciprocal translocations

Empirical Risk in Chromosome Inversions

Estimates the risk of viable unbalanced offspring for inversion carriers

Gail Model — Breast Cancer Risk (BCRAT)

Estimates 5-year and lifetime risk of invasive breast cancer using validated clinical factors

Haploid Autosomal Length (HAL) Calculator

Converts the physical portion of a chromosome arm into a percentage of the total autosomal genome

Hardy-Weinberg Carrier Risk

Calculates carrier frequency and reproductive risk for autosomal recessive diseases

ISCN Cytogenetic Nomenclature Parser

Decodes ISCN karyotype strings into plain-language clinical descriptions

NIPT Positive Predictive Value (PPV/NPV)

Calculates PPV and NPV of a cfDNA prenatal screening result using Bayes theorem

PENN II — BRCA1/2 Mutation Probability Score

Point-based score estimating prior probability of identifying a BRCA1 or BRCA2 pathogenic variant

Pharmacogenomic Dosing Advisor (CPIC / DPWG / FDA / EMA)

Genotype-guided dose, avoidance and switch recommendations across 60 drug–gene pairs

Post-Trisomy Recurrence Risk (Morris / Grande)

Estimates aneuploidy recurrence risk using complete age-specific lookup tables

Residual Carrier Risk (Negative Screen)

Post-test carrier probability after a negative screening result using Bayes theorem