GuiDeCode

Vasopressor Converter

Convert vasopressor doses between mcg/kg/min, mg/hr, and mL/hr.

Calculator

Loading calculator…

Why use it

Unit conversion errors for vasopressors are among the most dangerous medication errors in critical care. This tool standardizes dose communication and calculation.

About

Converts vasopressor/inotrope infusion rates between clinical dose units. Covers norepinephrine, epinephrine, dopamine, dobutamine, phenylephrine, and vasopressin. Essential for ICU and emergency settings.

When to use

  • Initiating or titrating vasopressor infusions in ICU/ED
  • Converting between mcg/kg/min and mL/hr for pump programming
  • Cross-checking orders when changing concentrations or patient weight
  • Teaching and cross-unit handoffs

Formula

mL/hr = (Dose_mcg_kg_min × Weight_kg × 60) / Concentration_mcg_mL mg/hr = Dose_mcg_kg_min × Weight_kg × 60 / 1000 mcg/kg/min = (mL/hr × Concentration_mcg_mL) / (Weight_kg × 60)

Pearls & pitfalls

  • Standard concentrations vary by institution — always verify your pharmacy preparation.
  • Norepinephrine: typical concentrations 4 mg/250 mL (16 mcg/mL) or 8 mg/250 mL (32 mcg/mL).
  • Dopamine: typically 400 mg/250 mL (1600 mcg/mL) or 200 mg/250 mL (800 mcg/mL).
  • Vasopressin is dosed in units/hr, not mcg/kg/min.
  • Epinephrine and norepinephrine: dose ≥0.25 mcg/kg/min is considered high-dose vasopressor support.

Next steps

Program infusion pump with calculated mL/hr. Always verify drug, concentration, and patient weight at bedside before starting or adjusting infusion.

Evidence

Derived from standard critical care pharmacology references and ASHP guidelines.

References

  1. ASHP. Guidelines on Handling Hazardous Drugs. AJHP. 2018. — link
  2. Hollenberg SM. Vasoactive drugs in circulatory shock. Am J Respir Crit Care Med. 2011;183(7):847-855. — link