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Mean Arterial Pressure (MAP)

Estimates average arterial pressure during a cardiac cycle

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Why use it

MAP is the primary hemodynamic target in septic shock and critical care management. It is more physiologically relevant than systolic BP for assessing organ perfusion. Used for vasopressor titration and hemodynamic monitoring.

About

Mean Arterial Pressure (MAP) represents the average arterial pressure throughout the cardiac cycle. It is considered a better indicator of tissue perfusion than systolic or diastolic pressure alone. MAP is a primary hemodynamic target in critical care, with most guidelines recommending MAP ≥ 65 mmHg to ensure adequate organ perfusion.

When to use

  • Hemodynamic monitoring in ICU and perioperative settings
  • Vasopressor titration targeting MAP ≥ 65 mmHg
  • Assessment of cerebral perfusion pressure (CPP = MAP - ICP)
  • Evaluation of shock states

Formula

MAP = Diastolic + ⅓ × (Systolic - Diastolic) Alternative: MAP = (SBP + 2 × DBP) / 3

Pearls & pitfalls

  • MAP = DBP + 1/3(SBP - DBP), reflecting that ~2/3 of the cardiac cycle is in diastole.
  • Target MAP ≥ 65 mmHg is recommended in septic shock (Surviving Sepsis Campaign).
  • In traumatic brain injury, MAP targets are higher to maintain CPP > 60-70 mmHg.
  • MAP measured by arterial line (gold standard) may differ from non-invasive cuff oscillometry.
  • Chronic hypertension patients may need higher MAP targets to maintain organ perfusion.

Next steps

MAP < 65: consider fluid resuscitation and/or vasopressors. MAP > 100-110: evaluate for hypertensive emergency. For cerebral perfusion, calculate CPP = MAP - ICP.

Evidence

Surviving Sepsis Campaign (2021) recommends initial target MAP ≥ 65 mmHg. SEPSISPAM trial showed no benefit to targeting MAP 80-85 vs 65-70 except in chronic hypertension subgroup.

References

  1. Evans L et al. Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2021. Crit Care Med. 2021;49(11):e1063-e1143. — link
  2. Asfar P et al. High versus low blood-pressure target in patients with septic shock. N Engl J Med. 2014;370(17):1583-1593. — link