GuiDeCode

CURB-65

Community-acquired pneumonia severity score for disposition decisions

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Why use it

Simple bedside tool for pneumonia severity assessment. Guides admission decisions for CAP. Recommended by BTS and NICE guidelines. Requires only basic clinical and lab data.

About

CURB-65 is a clinical prediction rule for estimating mortality of community-acquired pneumonia (CAP) and guiding site-of-care decisions (outpatient vs. inpatient vs. ICU). It uses five simple criteria: Confusion, Urea, Respiratory rate, Blood pressure, and age ≥ 65.

When to use

  • Patients diagnosed with community-acquired pneumonia
  • Disposition decision: outpatient vs. hospital vs. ICU
  • Risk stratification at time of ED presentation

Formula

One point for each: C = Confusion (new onset) U = Urea > 7 mmol/L (BUN > 19.6 mg/dL) R = Respiratory rate ≥ 30/min B = Blood pressure (SBP < 90 or DBP ≤ 60 mmHg) 65 = Age ≥ 65 years

Pearls & pitfalls

  • CRB-65 (without urea) can be used when lab results are unavailable — useful in primary care.
  • CURB-65 may underestimate severity in young patients with severe sepsis.
  • Does not account for comorbidities, social factors, or oxygenation — use clinical judgment alongside.
  • PSI/PORT Score is an alternative that accounts for more variables but is more complex.
  • Consider ICU admission criteria separately (ATS/IDSA major/minor criteria).

Next steps

Score 0-1: Consider outpatient treatment. Score 2: Short inpatient stay or hospital-supervised outpatient. Score 3-5: Hospitalize; score 4-5 consider ICU admission.

Evidence

Derived from a multicentre study of 1,068 patients (Lim et al., Thorax 2003). Validated internationally. BTS/NICE recommended for CAP severity assessment. 30-day mortality ranges from <1% (score 0) to >40% (score 5).

References

  1. Lim WS et al. Defining community acquired pneumonia severity on presentation to hospital: an international derivation and validation study. Thorax. 2003;58(5):377-382. — link
  2. BTS Guidelines for the Management of Community Acquired Pneumonia in Adults. Thorax. 2009;64(Suppl III):iii1-iii55. — link